Ethylmagnesium Bromide CAS 925-90-6

Description

Ethylmagnesium Bromide, also known as EtMgBr, CAS 925-90-6,  is an indispensable and powerful reagent for organic chemistry. It allows the synthesis and preparation of many pharmaceuticals, specialty chemicals, and agrochemicals. Its versatility and reactivity make it an essential part of modern organic synthesis.

Ethylmagnesium Bromide EtMgBr CAS 925-90-6

Markets/Application:

Reactivity: Ethylmagnesium Bromide is highly reactive due to the magnesium-carbon bonds. It reacts readily with various organic molecules, including ketones, esters, aldehydes and other electrophilic substances. Its reactivity makes this reagent a valuable tool in organic synthesis.

Synthetic Applications: EtMgBr is used widely in organic synthesis, as a nucleophilic agent. It is used to introduce an ethyl ring into a molecule. This can be useful in building complex organic molecules. The Grignard Reagents are essential tools for organic chemistry to create carbon-carbon bonds.

Preparation: Ethylmagnesium Bromide EtMgBr is usually prepared by reacting Diethyl Ether (Et2O), magnesium metal (Mg), and ethyl chloride (C2H5Br), in a controlled atmosphere, often in anhydrous conditions (without water).

Safety precautions: Ethylmagnesium Bromide EtMgBr can catch fire spontaneously when exposed to the air. It is highly reactive, pyrophoric and volatile. It must be handled carefully due to its potential hazards and reactivity. This is usually done in an inert, dry atmosphere such as in a glove box or under nitrogen or argon gas. When working with this substance, it is essential to take the necessary safety precautions, such as wearing protective gear.

Applications: Ethylmagnesium Bromide EtMgBr can be used for a variety of chemical reactions. These include nucleophilic additions of carbonyl compounds to form carbon-carbon bonds and in various transformations of organic synthesis. It is a versatile and useful reagent in both the chemical and laboratory industries.

Synonyms:

EtMgBr

Bromoethylmagnesium

Ethvlmagnesiumbromide

Ethylmagnesium bromide

Magnesium, bromoethyl-

Ethyl magnesium bromide

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